Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma
Identifieur interne : 002183 ( Main/Exploration ); précédent : 002182; suivant : 002184Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma
Auteurs : Siyuan Zheng [États-Unis] ; Andrew D. Cherniack [États-Unis] ; Ninad Dewal [États-Unis] ; Richard A. Moffitt [États-Unis] ; Ludmila Danilova [États-Unis] ; Bradley A. Murray [États-Unis] ; Antonio M. Lerario [Brésil, États-Unis] ; Tobias Else [États-Unis] ; Theo A. Knijnenburg [États-Unis] ; Giovanni Ciriello [Suisse, États-Unis] ; Seungchan Kim [États-Unis] ; Guillaume Assie [France] ; Olena Morozova [États-Unis] ; Rehan Akbani [États-Unis] ; Juliann Shih [États-Unis] ; Katherine A. Hoadley [États-Unis] ; Toni K. Choueiri [États-Unis] ; Jens Waldmann [Allemagne] ; Ozgur Mete [Canada] ; A. Gordon Robertson [Canada] ; Hsin-Ta Wu [États-Unis] ; Benjamin J. Raphael [États-Unis] ; Lina Shao [États-Unis] ; Matthew Meyerson [États-Unis] ; Michael J. Demeure [États-Unis] ; Felix Beuschlein [Allemagne] ; Anthony J. Gill [Australie] ; Stan B. Sidhu [Australie] ; Madson Q. Almeida [Brésil] ; Maria C. B. V. Fragoso [Brésil] ; Leslie M. Cope [États-Unis] ; Electron Kebebew [États-Unis] ; Mouhammed A. Habra [États-Unis] ; Timothy G. Whitsett [États-Unis] ; Kimberly J. Bussey [États-Unis] ; William E. Rainey [États-Unis] ; Sylvia L. Asa [Canada] ; Jérôme Bertherat [France] ; Martin Fassnacht [Allemagne] ; David A. Wheeler [États-Unis] ; Gary D. Hammer [États-Unis] ; Thomas J. Giordano [États-Unis] ; Roel G. W. Verhaak [États-Unis]Source :
- Cancer cell [ 1535-6108 ] ; 2016.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Analyse de profil d'expression de gènes (), Carcinome corticosurrénalien (), Carcinome corticosurrénalien (anatomopathologie), Carcinome corticosurrénalien (génétique), Enfant, Femelle, Génome humain (génétique), Génomique (), Humains, Jeune adulte, Mutation, Mâle, Méthylation de l'ADN, Pronostic, Prédisposition génétique à une maladie (génétique), Régulation de l'expression des gènes tumoraux, Sujet âgé, Sujet âgé de 80 ans ou plus, Survie sans rechute, Tumeurs corticosurrénaliennes (), Tumeurs corticosurrénaliennes (anatomopathologie), Tumeurs corticosurrénaliennes (génétique), Évaluation de résultat (soins).
- MESH :
- anatomopathologie : Carcinome corticosurrénalien, Tumeurs corticosurrénaliennes.
- génétique : Carcinome corticosurrénalien, Génome humain, Prédisposition génétique à une maladie, Tumeurs corticosurrénaliennes.
- Adolescent, Adulte, Adulte d'âge moyen, Analyse de profil d'expression de gènes, Carcinome corticosurrénalien, Enfant, Femelle, Génomique, Humains, Jeune adulte, Mutation, Mâle, Méthylation de l'ADN, Pronostic, Régulation de l'expression des gènes tumoraux, Sujet âgé, Sujet âgé de 80 ans ou plus, Survie sans rechute, Tumeurs corticosurrénaliennes, Évaluation de résultat (soins).
English descriptors
- KwdEn :
- Adolescent, Adrenal Cortex Neoplasms (genetics), Adrenal Cortex Neoplasms (pathology), Adrenal Cortex Neoplasms (therapy), Adrenocortical Carcinoma (genetics), Adrenocortical Carcinoma (pathology), Adrenocortical Carcinoma (therapy), Adult, Aged, Aged, 80 and over, Child, DNA Methylation, Disease-Free Survival, Female, Gene Expression Profiling (methods), Gene Expression Regulation, Neoplastic, Genetic Predisposition to Disease (genetics), Genome, Human (genetics), Genomics (methods), Humans, Male, Middle Aged, Mutation, Outcome Assessment (Health Care), Prognosis, Young Adult.
- MESH :
- genetics : Adrenal Cortex Neoplasms, Adrenocortical Carcinoma, Genetic Predisposition to Disease, Genome, Human.
- methods : Gene Expression Profiling, Genomics.
- pathology : Adrenal Cortex Neoplasms, Adrenocortical Carcinoma.
- therapy : Adrenal Cortex Neoplasms, Adrenocortical Carcinoma.
- Adolescent, Adult, Aged, Aged, 80 and over, Child, DNA Methylation, Disease-Free Survival, Female, Gene Expression Regulation, Neoplastic, Humans, Male, Middle Aged, Mutation, Outcome Assessment (Health Care), Prognosis, Young Adult.
Abstract
We describe a comprehensive genomic characterization of adrenocortical carcinoma (ACC). Using this dataset, we expand the catalogue of known ACC driver genes to include
Url:
DOI: 10.1016/j.ccell.2016.04.002
PubMed: 27165744
PubMed Central: 4864952
Affiliations:
- Allemagne, Australie, Brésil, Canada, France, Suisse, États-Unis
- Arizona, Bavière, Californie, Canton de Vaud, Caroline du Nord, District de Basse-Franconie, District de Haute-Bavière, Maryland, Massachusetts, Michigan, Nouvelle-Galles du Sud, Rhode Island, Texas, Washington (État), État de New York, État de São Paulo, Île-de-France
- Chapel Hill (Caroline du Nord), Lausanne, Munich, Paris, Providence (Rhode Island), Sydney, São Paulo, Wurtzbourg
- Université Brown, Université Louis-et-Maximilien de Munich, Université Paris-Descartes, Université de Caroline du Nord à Chapel Hill, Université de Sydney, Université de São Paulo
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Le document en format XML
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Knijnenburg</name><affiliation wicri:level="2"><nlm:aff id="A10">Institute for Systems Biology, Seattle, WA 98109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Ciriello, Giovanni" sort="Ciriello, Giovanni" uniqKey="Ciriello G" first="Giovanni" last="Ciriello">Giovanni Ciriello</name><affiliation wicri:level="1"><nlm:aff id="A11">Department of Computational Biology, University of Lausanne, Rue du Bugnon 27, 1005 Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Computational Biology, University of Lausanne, Rue du Bugnon 27, 1005 Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A12">Computational Biology Center, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Computational Biology Center, Memorial Sloan-Kettering Cancer Center, New York, NY 10065</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Kim, Seungchan" sort="Kim, Seungchan" uniqKey="Kim S" first="Seungchan" last="Kim">Seungchan Kim</name><affiliation wicri:level="2"><nlm:aff id="A13">Translational Genomics Research Institute, Phoenix, AZ 85004, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Genomics Research Institute, Phoenix, AZ 85004</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Assie, Guillaume" sort="Assie, Guillaume" uniqKey="Assie G" first="Guillaume" last="Assie">Guillaume Assie</name><affiliation wicri:level="3"><nlm:aff id="A14">Inserm U1016, CNRS UMR 8104, Institut Cochin, 75014 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Inserm U1016, CNRS UMR 8104, Institut Cochin, 75014 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A15">Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, 75006 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, 75006 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Paris-Descartes</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">Department of Endocrinology, Referral Center for Rare Adrenal Diseases, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, 75014 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Endocrinology, Referral Center for Rare Adrenal Diseases, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, 75014 Paris</wicri:regionArea><wicri:noRegion>75014 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation><nlm:aff id="A17">European Network for the Study of Adrenal Tumors</nlm:aff></affiliation></author><author><name sortKey="Morozova, Olena" sort="Morozova, Olena" uniqKey="Morozova O" first="Olena" last="Morozova">Olena Morozova</name><affiliation wicri:level="2"><nlm:aff id="A18">University of California Santa Cruz Genomics Institute, University California Santa Cruz, Santa Cruz, CA 95064, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of California Santa Cruz Genomics Institute, University California Santa Cruz, Santa Cruz, CA 95064</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Akbani, Rehan" sort="Akbani, Rehan" uniqKey="Akbani R" first="Rehan" last="Akbani">Rehan Akbani</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Shih, Juliann" sort="Shih, Juliann" uniqKey="Shih J" first="Juliann" last="Shih">Juliann Shih</name><affiliation wicri:level="2"><nlm:aff id="A2">The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A3">Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Hoadley, Katherine A" sort="Hoadley, Katherine A" uniqKey="Hoadley K" first="Katherine A." last="Hoadley">Katherine A. Hoadley</name><affiliation wicri:level="4"><nlm:aff id="A5">Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599</wicri:regionArea><placeName><region type="state">Caroline du Nord</region><settlement type="city">Chapel Hill (Caroline du Nord)</settlement></placeName><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName></affiliation></author><author><name sortKey="Choueiri, Toni K" sort="Choueiri, Toni K" uniqKey="Choueiri T" first="Toni K." last="Choueiri">Toni K. Choueiri</name><affiliation wicri:level="2"><nlm:aff id="A2">The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A19">Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Waldmann, Jens" sort="Waldmann, Jens" uniqKey="Waldmann J" first="Jens" last="Waldmann">Jens Waldmann</name><affiliation><nlm:aff id="A17">European Network for the Study of Adrenal Tumors</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="A20">Department of Visceral, Thoracic and Vascular Surgery, University Hospital Giessen and Marburg, Campus Marburg, General Surgery, Endocrine Center, 34501 Marburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Visceral, Thoracic and Vascular Surgery, University Hospital Giessen and Marburg, Campus Marburg, General Surgery, Endocrine Center, 34501 Marburg</wicri:regionArea><wicri:noRegion>34501 Marburg</wicri:noRegion><wicri:noRegion>34501 Marburg</wicri:noRegion><wicri:noRegion>34501 Marburg</wicri:noRegion></affiliation></author><author><name sortKey="Mete, Ozgur" sort="Mete, Ozgur" uniqKey="Mete O" first="Ozgur" last="Mete">Ozgur Mete</name><affiliation wicri:level="1"><nlm:aff id="A21">Department of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario M5G 2C4, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario M5G 2C4</wicri:regionArea><wicri:noRegion>Ontario M5G 2C4</wicri:noRegion></affiliation></author><author><name sortKey="Robertson, A Gordon" sort="Robertson, A Gordon" uniqKey="Robertson A" first="A. Gordon" last="Robertson">A. Gordon Robertson</name><affiliation wicri:level="1"><nlm:aff id="A22">Canada’s Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC V5Z 4S6, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Canada’s Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC V5Z 4S6</wicri:regionArea><wicri:noRegion>BC V5Z 4S6</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Hsin Ta" sort="Wu, Hsin Ta" uniqKey="Wu H" first="Hsin-Ta" last="Wu">Hsin-Ta Wu</name><affiliation wicri:level="4"><nlm:aff id="A23">Department of Computer Science, Brown University, Providence, RI 02906, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Computer Science, Brown University, Providence, RI 02906</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Raphael, Benjamin J" sort="Raphael, Benjamin J" uniqKey="Raphael B" first="Benjamin J." last="Raphael">Benjamin J. Raphael</name><affiliation wicri:level="4"><nlm:aff id="A23">Department of Computer Science, Brown University, Providence, RI 02906, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Computer Science, Brown University, Providence, RI 02906</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Shao, Lina" sort="Shao, Lina" uniqKey="Shao L" first="Lina" last="Shao">Lina Shao</name><affiliation wicri:level="2"><nlm:aff id="A8">Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Meyerson, Matthew" sort="Meyerson, Matthew" uniqKey="Meyerson M" first="Matthew" last="Meyerson">Matthew Meyerson</name><affiliation wicri:level="2"><nlm:aff id="A2">The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A3">Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A24">Department of Pathology, Harvard Medical School, Boston, Massachusetts 02215, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, Harvard Medical School, Boston, Massachusetts 02215</wicri:regionArea><wicri:noRegion>Massachusetts 02215</wicri:noRegion></affiliation></author><author><name sortKey="Demeure, Michael J" sort="Demeure, Michael J" uniqKey="Demeure M" first="Michael J." last="Demeure">Michael J. Demeure</name><affiliation wicri:level="2"><nlm:aff id="A13">Translational Genomics Research Institute, Phoenix, AZ 85004, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Genomics Research Institute, Phoenix, AZ 85004</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Beuschlein, Felix" sort="Beuschlein, Felix" uniqKey="Beuschlein F" first="Felix" last="Beuschlein">Felix Beuschlein</name><affiliation><nlm:aff id="A17">European Network for the Study of Adrenal Tumors</nlm:aff></affiliation><affiliation wicri:level="4"><nlm:aff id="A25">Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, D-80336 Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, D-80336 Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Gill, Anthony J" sort="Gill, Anthony J" uniqKey="Gill A" first="Anthony J." last="Gill">Anthony J. Gill</name><affiliation wicri:level="4"><nlm:aff id="A26">University of Sydney, Australia NSW 2006, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>University of Sydney, Australia NSW 2006</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A27">Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW 2065</wicri:regionArea><wicri:noRegion>NSW 2065</wicri:noRegion></affiliation></author><author><name sortKey="Sidhu, Stan B" sort="Sidhu, Stan B" uniqKey="Sidhu S" first="Stan B." last="Sidhu">Stan B. Sidhu</name><affiliation wicri:level="4"><nlm:aff id="A26">University of Sydney, Australia NSW 2006, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>University of Sydney, Australia NSW 2006</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A28">Endocrine Surgical Unit, Royal North Shore Hospital, St Leonards, NSW 2065, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Endocrine Surgical Unit, Royal North Shore Hospital, St Leonards, NSW 2065</wicri:regionArea><wicri:noRegion>NSW 2065</wicri:noRegion></affiliation></author><author><name sortKey="Almeida, Madson Q" sort="Almeida, Madson Q" uniqKey="Almeida M" first="Madson Q." last="Almeida">Madson Q. Almeida</name><affiliation wicri:level="4"><nlm:aff id="A7">Unidade de Suprarrenal, Laboratório de Hormônios e Genética Molecular LIM42, Serviço de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Unidade de Suprarrenal, Laboratório de Hormônios e Genética Molecular LIM42, Serviço de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A29">Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Fragoso, Maria C B V" sort="Fragoso, Maria C B V" uniqKey="Fragoso M" first="Maria C. B. V." last="Fragoso">Maria C. B. V. Fragoso</name><affiliation wicri:level="4"><nlm:aff id="A7">Unidade de Suprarrenal, Laboratório de Hormônios e Genética Molecular LIM42, Serviço de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Unidade de Suprarrenal, Laboratório de Hormônios e Genética Molecular LIM42, Serviço de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A29">Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Cope, Leslie M" sort="Cope, Leslie M" uniqKey="Cope L" first="Leslie M." last="Cope">Leslie M. Cope</name><affiliation wicri:level="2"><nlm:aff id="A6">The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kebebew, Electron" sort="Kebebew, Electron" uniqKey="Kebebew E" first="Electron" last="Kebebew">Electron Kebebew</name><affiliation wicri:level="2"><nlm:aff id="A30">Endocrine Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda 20892, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Endocrine Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda 20892, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Habra, Mouhammed A" sort="Habra, Mouhammed A" uniqKey="Habra M" first="Mouhammed A." last="Habra">Mouhammed A. Habra</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Whitsett, Timothy G" sort="Whitsett, Timothy G" uniqKey="Whitsett T" first="Timothy G." last="Whitsett">Timothy G. Whitsett</name><affiliation wicri:level="2"><nlm:aff id="A13">Translational Genomics Research Institute, Phoenix, AZ 85004, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Genomics Research Institute, Phoenix, AZ 85004</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Bussey, Kimberly J" sort="Bussey, Kimberly J" uniqKey="Bussey K" first="Kimberly J." last="Bussey">Kimberly J. Bussey</name><affiliation wicri:level="2"><nlm:aff id="A13">Translational Genomics Research Institute, Phoenix, AZ 85004, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Genomics Research Institute, Phoenix, AZ 85004</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A31">NantOmics, LLC, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287-5001, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>NantOmics, LLC, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287-5001</wicri:regionArea><wicri:noRegion>85287-5001</wicri:noRegion></affiliation></author><author><name sortKey="Rainey, William E" sort="Rainey, William E" uniqKey="Rainey W" first="William E." last="Rainey">William E. Rainey</name><affiliation wicri:level="2"><nlm:aff id="A8">Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Asa, Sylvia L" sort="Asa, Sylvia L" uniqKey="Asa S" first="Sylvia L." last="Asa">Sylvia L. Asa</name><affiliation wicri:level="1"><nlm:aff id="A21">Department of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario M5G 2C4, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario M5G 2C4</wicri:regionArea><wicri:noRegion>Ontario M5G 2C4</wicri:noRegion></affiliation></author><author><name sortKey="Bertherat, Jerome" sort="Bertherat, Jerome" uniqKey="Bertherat J" first="Jérôme" last="Bertherat">Jérôme Bertherat</name><affiliation wicri:level="1"><nlm:aff id="A14">Inserm U1016, CNRS UMR 8104, Institut Cochin, 75014 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Inserm U1016, CNRS UMR 8104, Institut Cochin, 75014 Paris</wicri:regionArea><wicri:noRegion>75014 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A15">Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, 75006 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, 75006 Paris</wicri:regionArea><wicri:noRegion>75006 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Paris-Descartes</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">Department of Endocrinology, Referral Center for Rare Adrenal Diseases, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, 75014 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Endocrinology, Referral Center for Rare Adrenal Diseases, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, 75014 Paris</wicri:regionArea><wicri:noRegion>75014 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation><nlm:aff id="A17">European Network for the Study of Adrenal Tumors</nlm:aff></affiliation></author><author><name sortKey="Fassnacht, Martin" sort="Fassnacht, Martin" uniqKey="Fassnacht M" first="Martin" last="Fassnacht">Martin Fassnacht</name><affiliation><nlm:aff id="A17">European Network for the Study of Adrenal Tumors</nlm:aff></affiliation><affiliation wicri:level="3"><nlm:aff id="A32">Department of Internal Medicine I, Endocrine and Diabetes Unit, University Hospital Würzburg, 97080 Würzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine I, Endocrine and Diabetes Unit, University Hospital Würzburg, 97080 Würzburg</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Basse-Franconie</region><settlement type="city">Wurtzbourg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A33">Comprehensive Cancer Center Mainfranken, University of Würzburg, 97080 Würzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Comprehensive Cancer Center Mainfranken, University of Würzburg, 97080 Würzburg</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Basse-Franconie</region><settlement type="city">Wurtzbourg</settlement></placeName></affiliation></author><author><name sortKey="Wheeler, David A" sort="Wheeler, David A" uniqKey="Wheeler D" first="David A." last="Wheeler">David A. Wheeler</name><affiliation wicri:level="2"><nlm:aff id="A4">Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Hammer, Gary D" sort="Hammer, Gary D" uniqKey="Hammer G" first="Gary D." last="Hammer">Gary D. Hammer</name><affiliation wicri:level="2"><nlm:aff id="A8">Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Giordano, Thomas J" sort="Giordano, Thomas J" uniqKey="Giordano T" first="Thomas J." last="Giordano">Thomas J. Giordano</name><affiliation wicri:level="2"><nlm:aff id="A8">Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Verhaak, Roel G W" sort="Verhaak, Roel G W" uniqKey="Verhaak R" first="Roel G. W." last="Verhaak">Roel G. W. Verhaak</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27165744</idno><idno type="pmc">4864952</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864952</idno><idno type="RBID">PMC:4864952</idno><idno type="doi">10.1016/j.ccell.2016.04.002</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">001E03</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001E03</idno><idno type="wicri:Area/Pmc/Curation">001C59</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001C59</idno><idno type="wicri:Area/Pmc/Checkpoint">000A55</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000A55</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">001E52</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001E52</idno><idno type="wicri:Area/PubMed/Curation">001E28</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001E28</idno><idno type="wicri:Area/PubMed/Checkpoint">001E28</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001E28</idno><idno type="wicri:Area/Ncbi/Merge">003532</idno><idno type="wicri:Area/Ncbi/Curation">003532</idno><idno type="wicri:Area/Ncbi/Checkpoint">003532</idno><idno type="wicri:doubleKey">1535-6108:2016:Zheng S:comprehensive:pan:genomic</idno><idno type="wicri:Area/Main/Merge">002182</idno><idno type="wicri:Area/Main/Curation">002183</idno><idno type="wicri:Area/Main/Exploration">002183</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma</title><author><name sortKey="Zheng, Siyuan" sort="Zheng, Siyuan" uniqKey="Zheng S" first="Siyuan" last="Zheng">Siyuan Zheng</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Cherniack, Andrew D" sort="Cherniack, Andrew D" uniqKey="Cherniack A" first="Andrew D." last="Cherniack">Andrew D. Cherniack</name><affiliation wicri:level="2"><nlm:aff id="A2">The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A3">Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Dewal, Ninad" sort="Dewal, Ninad" uniqKey="Dewal N" first="Ninad" last="Dewal">Ninad Dewal</name><affiliation wicri:level="2"><nlm:aff id="A4">Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Moffitt, Richard A" sort="Moffitt, Richard A" uniqKey="Moffitt R" first="Richard A." last="Moffitt">Richard A. Moffitt</name><affiliation wicri:level="4"><nlm:aff id="A5">Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599</wicri:regionArea><placeName><region type="state">Caroline du Nord</region><settlement type="city">Chapel Hill (Caroline du Nord)</settlement></placeName><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName></affiliation></author><author><name sortKey="Danilova, Ludmila" sort="Danilova, Ludmila" uniqKey="Danilova L" first="Ludmila" last="Danilova">Ludmila Danilova</name><affiliation wicri:level="2"><nlm:aff id="A6">The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Murray, Bradley A" sort="Murray, Bradley A" uniqKey="Murray B" first="Bradley A." last="Murray">Bradley A. Murray</name><affiliation wicri:level="2"><nlm:aff id="A2">The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A3">Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A4">Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Lerario, Antonio M" sort="Lerario, Antonio M" uniqKey="Lerario A" first="Antonio M." last="Lerario">Antonio M. Lerario</name><affiliation wicri:level="4"><nlm:aff id="A7">Unidade de Suprarrenal, Laboratório de Hormônios e Genética Molecular LIM42, Serviço de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Unidade de Suprarrenal, Laboratório de Hormônios e Genética Molecular LIM42, Serviço de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A8">Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Else, Tobias" sort="Else, Tobias" uniqKey="Else T" first="Tobias" last="Else">Tobias Else</name><affiliation wicri:level="2"><nlm:aff id="A8">Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Knijnenburg, Theo A" sort="Knijnenburg, Theo A" uniqKey="Knijnenburg T" first="Theo A." last="Knijnenburg">Theo A. Knijnenburg</name><affiliation wicri:level="2"><nlm:aff id="A10">Institute for Systems Biology, Seattle, WA 98109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Systems Biology, Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Ciriello, Giovanni" sort="Ciriello, Giovanni" uniqKey="Ciriello G" first="Giovanni" last="Ciriello">Giovanni Ciriello</name><affiliation wicri:level="1"><nlm:aff id="A11">Department of Computational Biology, University of Lausanne, Rue du Bugnon 27, 1005 Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Computational Biology, University of Lausanne, Rue du Bugnon 27, 1005 Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A12">Computational Biology Center, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Computational Biology Center, Memorial Sloan-Kettering Cancer Center, New York, NY 10065</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Kim, Seungchan" sort="Kim, Seungchan" uniqKey="Kim S" first="Seungchan" last="Kim">Seungchan Kim</name><affiliation wicri:level="2"><nlm:aff id="A13">Translational Genomics Research Institute, Phoenix, AZ 85004, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Genomics Research Institute, Phoenix, AZ 85004</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Assie, Guillaume" sort="Assie, Guillaume" uniqKey="Assie G" first="Guillaume" last="Assie">Guillaume Assie</name><affiliation wicri:level="3"><nlm:aff id="A14">Inserm U1016, CNRS UMR 8104, Institut Cochin, 75014 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Inserm U1016, CNRS UMR 8104, Institut Cochin, 75014 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A15">Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, 75006 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, 75006 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Paris-Descartes</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">Department of Endocrinology, Referral Center for Rare Adrenal Diseases, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, 75014 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Endocrinology, Referral Center for Rare Adrenal Diseases, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, 75014 Paris</wicri:regionArea><wicri:noRegion>75014 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation><nlm:aff id="A17">European Network for the Study of Adrenal Tumors</nlm:aff></affiliation></author><author><name sortKey="Morozova, Olena" sort="Morozova, Olena" uniqKey="Morozova O" first="Olena" last="Morozova">Olena Morozova</name><affiliation wicri:level="2"><nlm:aff id="A18">University of California Santa Cruz Genomics Institute, University California Santa Cruz, Santa Cruz, CA 95064, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of California Santa Cruz Genomics Institute, University California Santa Cruz, Santa Cruz, CA 95064</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Akbani, Rehan" sort="Akbani, Rehan" uniqKey="Akbani R" first="Rehan" last="Akbani">Rehan Akbani</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Shih, Juliann" sort="Shih, Juliann" uniqKey="Shih J" first="Juliann" last="Shih">Juliann Shih</name><affiliation wicri:level="2"><nlm:aff id="A2">The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A3">Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Hoadley, Katherine A" sort="Hoadley, Katherine A" uniqKey="Hoadley K" first="Katherine A." last="Hoadley">Katherine A. Hoadley</name><affiliation wicri:level="4"><nlm:aff id="A5">Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599</wicri:regionArea><placeName><region type="state">Caroline du Nord</region><settlement type="city">Chapel Hill (Caroline du Nord)</settlement></placeName><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName></affiliation></author><author><name sortKey="Choueiri, Toni K" sort="Choueiri, Toni K" uniqKey="Choueiri T" first="Toni K." last="Choueiri">Toni K. Choueiri</name><affiliation wicri:level="2"><nlm:aff id="A2">The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A19">Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Waldmann, Jens" sort="Waldmann, Jens" uniqKey="Waldmann J" first="Jens" last="Waldmann">Jens Waldmann</name><affiliation><nlm:aff id="A17">European Network for the Study of Adrenal Tumors</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="A20">Department of Visceral, Thoracic and Vascular Surgery, University Hospital Giessen and Marburg, Campus Marburg, General Surgery, Endocrine Center, 34501 Marburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Visceral, Thoracic and Vascular Surgery, University Hospital Giessen and Marburg, Campus Marburg, General Surgery, Endocrine Center, 34501 Marburg</wicri:regionArea><wicri:noRegion>34501 Marburg</wicri:noRegion><wicri:noRegion>34501 Marburg</wicri:noRegion><wicri:noRegion>34501 Marburg</wicri:noRegion></affiliation></author><author><name sortKey="Mete, Ozgur" sort="Mete, Ozgur" uniqKey="Mete O" first="Ozgur" last="Mete">Ozgur Mete</name><affiliation wicri:level="1"><nlm:aff id="A21">Department of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario M5G 2C4, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario M5G 2C4</wicri:regionArea><wicri:noRegion>Ontario M5G 2C4</wicri:noRegion></affiliation></author><author><name sortKey="Robertson, A Gordon" sort="Robertson, A Gordon" uniqKey="Robertson A" first="A. Gordon" last="Robertson">A. Gordon Robertson</name><affiliation wicri:level="1"><nlm:aff id="A22">Canada’s Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC V5Z 4S6, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Canada’s Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC V5Z 4S6</wicri:regionArea><wicri:noRegion>BC V5Z 4S6</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Hsin Ta" sort="Wu, Hsin Ta" uniqKey="Wu H" first="Hsin-Ta" last="Wu">Hsin-Ta Wu</name><affiliation wicri:level="4"><nlm:aff id="A23">Department of Computer Science, Brown University, Providence, RI 02906, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Computer Science, Brown University, Providence, RI 02906</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Raphael, Benjamin J" sort="Raphael, Benjamin J" uniqKey="Raphael B" first="Benjamin J." last="Raphael">Benjamin J. Raphael</name><affiliation wicri:level="4"><nlm:aff id="A23">Department of Computer Science, Brown University, Providence, RI 02906, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Computer Science, Brown University, Providence, RI 02906</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Shao, Lina" sort="Shao, Lina" uniqKey="Shao L" first="Lina" last="Shao">Lina Shao</name><affiliation wicri:level="2"><nlm:aff id="A8">Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Meyerson, Matthew" sort="Meyerson, Matthew" uniqKey="Meyerson M" first="Matthew" last="Meyerson">Matthew Meyerson</name><affiliation wicri:level="2"><nlm:aff id="A2">The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A3">Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A24">Department of Pathology, Harvard Medical School, Boston, Massachusetts 02215, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, Harvard Medical School, Boston, Massachusetts 02215</wicri:regionArea><wicri:noRegion>Massachusetts 02215</wicri:noRegion></affiliation></author><author><name sortKey="Demeure, Michael J" sort="Demeure, Michael J" uniqKey="Demeure M" first="Michael J." last="Demeure">Michael J. Demeure</name><affiliation wicri:level="2"><nlm:aff id="A13">Translational Genomics Research Institute, Phoenix, AZ 85004, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Genomics Research Institute, Phoenix, AZ 85004</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Beuschlein, Felix" sort="Beuschlein, Felix" uniqKey="Beuschlein F" first="Felix" last="Beuschlein">Felix Beuschlein</name><affiliation><nlm:aff id="A17">European Network for the Study of Adrenal Tumors</nlm:aff></affiliation><affiliation wicri:level="4"><nlm:aff id="A25">Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, D-80336 Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, D-80336 Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Gill, Anthony J" sort="Gill, Anthony J" uniqKey="Gill A" first="Anthony J." last="Gill">Anthony J. Gill</name><affiliation wicri:level="4"><nlm:aff id="A26">University of Sydney, Australia NSW 2006, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>University of Sydney, Australia NSW 2006</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A27">Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW 2065</wicri:regionArea><wicri:noRegion>NSW 2065</wicri:noRegion></affiliation></author><author><name sortKey="Sidhu, Stan B" sort="Sidhu, Stan B" uniqKey="Sidhu S" first="Stan B." last="Sidhu">Stan B. Sidhu</name><affiliation wicri:level="4"><nlm:aff id="A26">University of Sydney, Australia NSW 2006, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>University of Sydney, Australia NSW 2006</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A28">Endocrine Surgical Unit, Royal North Shore Hospital, St Leonards, NSW 2065, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Endocrine Surgical Unit, Royal North Shore Hospital, St Leonards, NSW 2065</wicri:regionArea><wicri:noRegion>NSW 2065</wicri:noRegion></affiliation></author><author><name sortKey="Almeida, Madson Q" sort="Almeida, Madson Q" uniqKey="Almeida M" first="Madson Q." last="Almeida">Madson Q. Almeida</name><affiliation wicri:level="4"><nlm:aff id="A7">Unidade de Suprarrenal, Laboratório de Hormônios e Genética Molecular LIM42, Serviço de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Unidade de Suprarrenal, Laboratório de Hormônios e Genética Molecular LIM42, Serviço de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A29">Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Fragoso, Maria C B V" sort="Fragoso, Maria C B V" uniqKey="Fragoso M" first="Maria C. B. V." last="Fragoso">Maria C. B. V. Fragoso</name><affiliation wicri:level="4"><nlm:aff id="A7">Unidade de Suprarrenal, Laboratório de Hormônios e Genética Molecular LIM42, Serviço de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Unidade de Suprarrenal, Laboratório de Hormônios e Genética Molecular LIM42, Serviço de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A29">Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-900</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Cope, Leslie M" sort="Cope, Leslie M" uniqKey="Cope L" first="Leslie M." last="Cope">Leslie M. Cope</name><affiliation wicri:level="2"><nlm:aff id="A6">The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kebebew, Electron" sort="Kebebew, Electron" uniqKey="Kebebew E" first="Electron" last="Kebebew">Electron Kebebew</name><affiliation wicri:level="2"><nlm:aff id="A30">Endocrine Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda 20892, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Endocrine Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda 20892, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Habra, Mouhammed A" sort="Habra, Mouhammed A" uniqKey="Habra M" first="Mouhammed A." last="Habra">Mouhammed A. Habra</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Whitsett, Timothy G" sort="Whitsett, Timothy G" uniqKey="Whitsett T" first="Timothy G." last="Whitsett">Timothy G. Whitsett</name><affiliation wicri:level="2"><nlm:aff id="A13">Translational Genomics Research Institute, Phoenix, AZ 85004, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Genomics Research Institute, Phoenix, AZ 85004</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Bussey, Kimberly J" sort="Bussey, Kimberly J" uniqKey="Bussey K" first="Kimberly J." last="Bussey">Kimberly J. Bussey</name><affiliation wicri:level="2"><nlm:aff id="A13">Translational Genomics Research Institute, Phoenix, AZ 85004, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Genomics Research Institute, Phoenix, AZ 85004</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A31">NantOmics, LLC, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287-5001, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>NantOmics, LLC, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287-5001</wicri:regionArea><wicri:noRegion>85287-5001</wicri:noRegion></affiliation></author><author><name sortKey="Rainey, William E" sort="Rainey, William E" uniqKey="Rainey W" first="William E." last="Rainey">William E. Rainey</name><affiliation wicri:level="2"><nlm:aff id="A8">Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Asa, Sylvia L" sort="Asa, Sylvia L" uniqKey="Asa S" first="Sylvia L." last="Asa">Sylvia L. Asa</name><affiliation wicri:level="1"><nlm:aff id="A21">Department of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario M5G 2C4, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario M5G 2C4</wicri:regionArea><wicri:noRegion>Ontario M5G 2C4</wicri:noRegion></affiliation></author><author><name sortKey="Bertherat, Jerome" sort="Bertherat, Jerome" uniqKey="Bertherat J" first="Jérôme" last="Bertherat">Jérôme Bertherat</name><affiliation wicri:level="1"><nlm:aff id="A14">Inserm U1016, CNRS UMR 8104, Institut Cochin, 75014 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Inserm U1016, CNRS UMR 8104, Institut Cochin, 75014 Paris</wicri:regionArea><wicri:noRegion>75014 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A15">Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, 75006 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, 75006 Paris</wicri:regionArea><wicri:noRegion>75006 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Paris-Descartes</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">Department of Endocrinology, Referral Center for Rare Adrenal Diseases, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, 75014 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Endocrinology, Referral Center for Rare Adrenal Diseases, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, 75014 Paris</wicri:regionArea><wicri:noRegion>75014 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation><nlm:aff id="A17">European Network for the Study of Adrenal Tumors</nlm:aff></affiliation></author><author><name sortKey="Fassnacht, Martin" sort="Fassnacht, Martin" uniqKey="Fassnacht M" first="Martin" last="Fassnacht">Martin Fassnacht</name><affiliation><nlm:aff id="A17">European Network for the Study of Adrenal Tumors</nlm:aff></affiliation><affiliation wicri:level="3"><nlm:aff id="A32">Department of Internal Medicine I, Endocrine and Diabetes Unit, University Hospital Würzburg, 97080 Würzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine I, Endocrine and Diabetes Unit, University Hospital Würzburg, 97080 Würzburg</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Basse-Franconie</region><settlement type="city">Wurtzbourg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A33">Comprehensive Cancer Center Mainfranken, University of Würzburg, 97080 Würzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Comprehensive Cancer Center Mainfranken, University of Würzburg, 97080 Würzburg</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Basse-Franconie</region><settlement type="city">Wurtzbourg</settlement></placeName></affiliation></author><author><name sortKey="Wheeler, David A" sort="Wheeler, David A" uniqKey="Wheeler D" first="David A." last="Wheeler">David A. Wheeler</name><affiliation wicri:level="2"><nlm:aff id="A4">Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Hammer, Gary D" sort="Hammer, Gary D" uniqKey="Hammer G" first="Gary D." last="Hammer">Gary D. Hammer</name><affiliation wicri:level="2"><nlm:aff id="A8">Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Giordano, Thomas J" sort="Giordano, Thomas J" uniqKey="Giordano T" first="Thomas J." last="Giordano">Thomas J. Giordano</name><affiliation wicri:level="2"><nlm:aff id="A8">Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cell & Developmental Biology, Department of Pathology, Department of Molecular & Integrative Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Verhaak, Roel G W" sort="Verhaak, Roel G W" uniqKey="Verhaak R" first="Roel G. W." last="Verhaak">Roel G. W. Verhaak</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genomic Medicine, Department of Bioinformatics and Computational Biology, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author></analytic><series><title level="j">Cancer cell</title><idno type="ISSN">1535-6108</idno><idno type="eISSN">1878-3686</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adrenal Cortex Neoplasms (genetics)</term><term>Adrenal Cortex Neoplasms (pathology)</term><term>Adrenal Cortex Neoplasms (therapy)</term><term>Adrenocortical Carcinoma (genetics)</term><term>Adrenocortical Carcinoma (pathology)</term><term>Adrenocortical Carcinoma (therapy)</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Child</term><term>DNA Methylation</term><term>Disease-Free Survival</term><term>Female</term><term>Gene Expression Profiling (methods)</term><term>Gene Expression Regulation, Neoplastic</term><term>Genetic Predisposition to Disease (genetics)</term><term>Genome, Human (genetics)</term><term>Genomics (methods)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Mutation</term><term>Outcome Assessment (Health Care)</term><term>Prognosis</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Analyse de profil d'expression de gènes ()</term><term>Carcinome corticosurrénalien ()</term><term>Carcinome corticosurrénalien (anatomopathologie)</term><term>Carcinome corticosurrénalien (génétique)</term><term>Enfant</term><term>Femelle</term><term>Génome humain (génétique)</term><term>Génomique ()</term><term>Humains</term><term>Jeune adulte</term><term>Mutation</term><term>Mâle</term><term>Méthylation de l'ADN</term><term>Pronostic</term><term>Prédisposition génétique à une maladie (génétique)</term><term>Régulation de l'expression des gènes tumoraux</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Survie sans rechute</term><term>Tumeurs corticosurrénaliennes ()</term><term>Tumeurs corticosurrénaliennes (anatomopathologie)</term><term>Tumeurs corticosurrénaliennes (génétique)</term><term>Évaluation de résultat (soins)</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Carcinome corticosurrénalien</term><term>Tumeurs corticosurrénaliennes</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Adrenal Cortex Neoplasms</term><term>Adrenocortical Carcinoma</term><term>Genetic Predisposition to Disease</term><term>Genome, Human</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Carcinome corticosurrénalien</term><term>Génome humain</term><term>Prédisposition génétique à une maladie</term><term>Tumeurs corticosurrénaliennes</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Gene Expression Profiling</term><term>Genomics</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Adrenal Cortex Neoplasms</term><term>Adrenocortical Carcinoma</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Adrenal Cortex Neoplasms</term><term>Adrenocortical Carcinoma</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Child</term><term>DNA Methylation</term><term>Disease-Free Survival</term><term>Female</term><term>Gene Expression Regulation, Neoplastic</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Mutation</term><term>Outcome Assessment (Health Care)</term><term>Prognosis</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Analyse de profil d'expression de gènes</term><term>Carcinome corticosurrénalien</term><term>Enfant</term><term>Femelle</term><term>Génomique</term><term>Humains</term><term>Jeune adulte</term><term>Mutation</term><term>Mâle</term><term>Méthylation de l'ADN</term><term>Pronostic</term><term>Régulation de l'expression des gènes tumoraux</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Survie sans rechute</term><term>Tumeurs corticosurrénaliennes</term><term>Évaluation de résultat (soins)</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>SUMMARY</title><p id="P4">We describe a comprehensive genomic characterization of adrenocortical carcinoma (ACC). Using this dataset, we expand the catalogue of known ACC driver genes to include <italic>PRKAR1A</italic>, <italic>RPL22</italic>, <italic>TERF2</italic>, <italic>CCNE1</italic>, and <italic>NF1</italic>. Genome wide DNA copy number analysis revealed frequent occurrence of massive DNA loss followed by whole genome doubling (WGD) which was associated with aggressive clinical course, suggesting WGD is a hallmark of disease progression. Corroborating this hypothesis were increased <italic>TERT</italic> expression, decreased telomere length, and activation of cell cycle programs. Integrated subtype analysis identified three ACC subtypes with distinct clinical outcome and molecular alterations which could be captured by a 68 CpG probe DNA methylation signature, proposing a strategy for clinical stratification of patients based on molecular markers.</p></div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Brésil</li><li>Canada</li><li>France</li><li>Suisse</li><li>États-Unis</li></country><region><li>Arizona</li><li>Bavière</li><li>Californie</li><li>Canton de Vaud</li><li>Caroline du Nord</li><li>District de Basse-Franconie</li><li>District de Haute-Bavière</li><li>Maryland</li><li>Massachusetts</li><li>Michigan</li><li>Nouvelle-Galles du Sud</li><li>Rhode Island</li><li>Texas</li><li>Washington (État)</li><li>État de New York</li><li>État de São Paulo</li><li>Île-de-France</li></region><settlement><li>Chapel Hill (Caroline du Nord)</li><li>Lausanne</li><li>Munich</li><li>Paris</li><li>Providence (Rhode Island)</li><li>Sydney</li><li>São Paulo</li><li>Wurtzbourg</li></settlement><orgName><li>Université Brown</li><li>Université Louis-et-Maximilien de Munich</li><li>Université Paris-Descartes</li><li>Université de Caroline du Nord à Chapel Hill</li><li>Université de Sydney</li><li>Université de São Paulo</li></orgName></list><tree><country name="États-Unis"><region name="Texas"><name sortKey="Zheng, Siyuan" sort="Zheng, Siyuan" uniqKey="Zheng S" first="Siyuan" last="Zheng">Siyuan Zheng</name></region><name sortKey="Akbani, Rehan" sort="Akbani, Rehan" uniqKey="Akbani R" first="Rehan" last="Akbani">Rehan Akbani</name><name sortKey="Bussey, Kimberly J" sort="Bussey, Kimberly J" uniqKey="Bussey K" first="Kimberly J." last="Bussey">Kimberly J. Bussey</name><name sortKey="Bussey, Kimberly J" sort="Bussey, Kimberly J" uniqKey="Bussey K" first="Kimberly J." last="Bussey">Kimberly J. Bussey</name><name sortKey="Cherniack, Andrew D" sort="Cherniack, Andrew D" uniqKey="Cherniack A" first="Andrew D." last="Cherniack">Andrew D. Cherniack</name><name sortKey="Cherniack, Andrew D" sort="Cherniack, Andrew D" uniqKey="Cherniack A" first="Andrew D." last="Cherniack">Andrew D. Cherniack</name><name sortKey="Choueiri, Toni K" sort="Choueiri, Toni K" uniqKey="Choueiri T" first="Toni K." last="Choueiri">Toni K. Choueiri</name><name sortKey="Choueiri, Toni K" sort="Choueiri, Toni K" uniqKey="Choueiri T" first="Toni K." last="Choueiri">Toni K. Choueiri</name><name sortKey="Ciriello, Giovanni" sort="Ciriello, Giovanni" uniqKey="Ciriello G" first="Giovanni" last="Ciriello">Giovanni Ciriello</name><name sortKey="Cope, Leslie M" sort="Cope, Leslie M" uniqKey="Cope L" first="Leslie M." last="Cope">Leslie M. Cope</name><name sortKey="Danilova, Ludmila" sort="Danilova, Ludmila" uniqKey="Danilova L" first="Ludmila" last="Danilova">Ludmila Danilova</name><name sortKey="Demeure, Michael J" sort="Demeure, Michael J" uniqKey="Demeure M" first="Michael J." last="Demeure">Michael J. Demeure</name><name sortKey="Dewal, Ninad" sort="Dewal, Ninad" uniqKey="Dewal N" first="Ninad" last="Dewal">Ninad Dewal</name><name sortKey="Else, Tobias" sort="Else, Tobias" uniqKey="Else T" first="Tobias" last="Else">Tobias Else</name><name sortKey="Else, Tobias" sort="Else, Tobias" uniqKey="Else T" first="Tobias" last="Else">Tobias Else</name><name sortKey="Giordano, Thomas J" sort="Giordano, Thomas J" uniqKey="Giordano T" first="Thomas J." last="Giordano">Thomas J. Giordano</name><name sortKey="Giordano, Thomas J" sort="Giordano, Thomas J" uniqKey="Giordano T" first="Thomas J." last="Giordano">Thomas J. Giordano</name><name sortKey="Habra, Mouhammed A" sort="Habra, Mouhammed A" uniqKey="Habra M" first="Mouhammed A." last="Habra">Mouhammed A. Habra</name><name sortKey="Hammer, Gary D" sort="Hammer, Gary D" uniqKey="Hammer G" first="Gary D." last="Hammer">Gary D. Hammer</name><name sortKey="Hammer, Gary D" sort="Hammer, Gary D" uniqKey="Hammer G" first="Gary D." last="Hammer">Gary D. Hammer</name><name sortKey="Hoadley, Katherine A" sort="Hoadley, Katherine A" uniqKey="Hoadley K" first="Katherine A." last="Hoadley">Katherine A. Hoadley</name><name sortKey="Kebebew, Electron" sort="Kebebew, Electron" uniqKey="Kebebew E" first="Electron" last="Kebebew">Electron Kebebew</name><name sortKey="Kim, Seungchan" sort="Kim, Seungchan" uniqKey="Kim S" first="Seungchan" last="Kim">Seungchan Kim</name><name sortKey="Knijnenburg, Theo A" sort="Knijnenburg, Theo A" uniqKey="Knijnenburg T" first="Theo A." last="Knijnenburg">Theo A. Knijnenburg</name><name sortKey="Lerario, Antonio M" sort="Lerario, Antonio M" uniqKey="Lerario A" first="Antonio M." last="Lerario">Antonio M. Lerario</name><name sortKey="Lerario, Antonio M" sort="Lerario, Antonio M" uniqKey="Lerario A" first="Antonio M." last="Lerario">Antonio M. Lerario</name><name sortKey="Meyerson, Matthew" sort="Meyerson, Matthew" uniqKey="Meyerson M" first="Matthew" last="Meyerson">Matthew Meyerson</name><name sortKey="Meyerson, Matthew" sort="Meyerson, Matthew" uniqKey="Meyerson M" first="Matthew" last="Meyerson">Matthew Meyerson</name><name sortKey="Meyerson, Matthew" sort="Meyerson, Matthew" uniqKey="Meyerson M" first="Matthew" last="Meyerson">Matthew Meyerson</name><name sortKey="Moffitt, Richard A" sort="Moffitt, Richard A" uniqKey="Moffitt R" first="Richard A." last="Moffitt">Richard A. Moffitt</name><name sortKey="Morozova, Olena" sort="Morozova, Olena" uniqKey="Morozova O" first="Olena" last="Morozova">Olena Morozova</name><name sortKey="Murray, Bradley A" sort="Murray, Bradley A" uniqKey="Murray B" first="Bradley A." last="Murray">Bradley A. Murray</name><name sortKey="Murray, Bradley A" sort="Murray, Bradley A" uniqKey="Murray B" first="Bradley A." last="Murray">Bradley A. Murray</name><name sortKey="Murray, Bradley A" sort="Murray, Bradley A" uniqKey="Murray B" first="Bradley A." last="Murray">Bradley A. Murray</name><name sortKey="Rainey, William E" sort="Rainey, William E" uniqKey="Rainey W" first="William E." last="Rainey">William E. Rainey</name><name sortKey="Rainey, William E" sort="Rainey, William E" uniqKey="Rainey W" first="William E." last="Rainey">William E. Rainey</name><name sortKey="Raphael, Benjamin J" sort="Raphael, Benjamin J" uniqKey="Raphael B" first="Benjamin J." last="Raphael">Benjamin J. Raphael</name><name sortKey="Shao, Lina" sort="Shao, Lina" uniqKey="Shao L" first="Lina" last="Shao">Lina Shao</name><name sortKey="Shih, Juliann" sort="Shih, Juliann" uniqKey="Shih J" first="Juliann" last="Shih">Juliann Shih</name><name sortKey="Shih, Juliann" sort="Shih, Juliann" uniqKey="Shih J" first="Juliann" last="Shih">Juliann Shih</name><name sortKey="Verhaak, Roel G W" sort="Verhaak, Roel G W" uniqKey="Verhaak R" first="Roel G. W." last="Verhaak">Roel G. W. Verhaak</name><name sortKey="Wheeler, David A" sort="Wheeler, David A" uniqKey="Wheeler D" first="David A." last="Wheeler">David A. Wheeler</name><name sortKey="Whitsett, Timothy G" sort="Whitsett, Timothy G" uniqKey="Whitsett T" first="Timothy G." last="Whitsett">Timothy G. Whitsett</name><name sortKey="Wu, Hsin Ta" sort="Wu, Hsin Ta" uniqKey="Wu H" first="Hsin-Ta" last="Wu">Hsin-Ta Wu</name></country><country name="Brésil"><region name="État de São Paulo"><name sortKey="Lerario, Antonio M" sort="Lerario, Antonio M" uniqKey="Lerario A" first="Antonio M." last="Lerario">Antonio M. Lerario</name></region><name sortKey="Almeida, Madson Q" sort="Almeida, Madson Q" uniqKey="Almeida M" first="Madson Q." last="Almeida">Madson Q. Almeida</name><name sortKey="Almeida, Madson Q" sort="Almeida, Madson Q" uniqKey="Almeida M" first="Madson Q." last="Almeida">Madson Q. Almeida</name><name sortKey="Fragoso, Maria C B V" sort="Fragoso, Maria C B V" uniqKey="Fragoso M" first="Maria C. B. V." last="Fragoso">Maria C. B. V. Fragoso</name><name sortKey="Fragoso, Maria C B V" sort="Fragoso, Maria C B V" uniqKey="Fragoso M" first="Maria C. B. V." last="Fragoso">Maria C. B. V. Fragoso</name></country><country name="Suisse"><region name="Canton de Vaud"><name sortKey="Ciriello, Giovanni" sort="Ciriello, Giovanni" uniqKey="Ciriello G" first="Giovanni" last="Ciriello">Giovanni Ciriello</name></region></country><country name="France"><region name="Île-de-France"><name sortKey="Assie, Guillaume" sort="Assie, Guillaume" uniqKey="Assie G" first="Guillaume" last="Assie">Guillaume Assie</name></region><name sortKey="Assie, Guillaume" sort="Assie, Guillaume" uniqKey="Assie G" first="Guillaume" last="Assie">Guillaume Assie</name><name sortKey="Assie, Guillaume" sort="Assie, Guillaume" uniqKey="Assie G" first="Guillaume" last="Assie">Guillaume Assie</name><name sortKey="Bertherat, Jerome" sort="Bertherat, Jerome" uniqKey="Bertherat J" first="Jérôme" last="Bertherat">Jérôme Bertherat</name><name sortKey="Bertherat, Jerome" sort="Bertherat, Jerome" uniqKey="Bertherat J" first="Jérôme" last="Bertherat">Jérôme Bertherat</name><name sortKey="Bertherat, Jerome" sort="Bertherat, Jerome" uniqKey="Bertherat J" first="Jérôme" last="Bertherat">Jérôme Bertherat</name></country><country name="Allemagne"><noRegion><name sortKey="Waldmann, Jens" sort="Waldmann, Jens" uniqKey="Waldmann J" first="Jens" last="Waldmann">Jens Waldmann</name></noRegion><name sortKey="Beuschlein, Felix" sort="Beuschlein, Felix" uniqKey="Beuschlein F" first="Felix" last="Beuschlein">Felix Beuschlein</name><name sortKey="Fassnacht, Martin" sort="Fassnacht, Martin" uniqKey="Fassnacht M" first="Martin" last="Fassnacht">Martin Fassnacht</name><name sortKey="Fassnacht, Martin" sort="Fassnacht, Martin" uniqKey="Fassnacht M" first="Martin" last="Fassnacht">Martin Fassnacht</name></country><country name="Canada"><noRegion><name sortKey="Mete, Ozgur" sort="Mete, Ozgur" uniqKey="Mete O" first="Ozgur" last="Mete">Ozgur Mete</name></noRegion><name sortKey="Asa, Sylvia L" sort="Asa, Sylvia L" uniqKey="Asa S" first="Sylvia L." last="Asa">Sylvia L. Asa</name><name sortKey="Robertson, A Gordon" sort="Robertson, A Gordon" uniqKey="Robertson A" first="A. Gordon" last="Robertson">A. Gordon Robertson</name></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Gill, Anthony J" sort="Gill, Anthony J" uniqKey="Gill A" first="Anthony J." last="Gill">Anthony J. Gill</name></region><name sortKey="Gill, Anthony J" sort="Gill, Anthony J" uniqKey="Gill A" first="Anthony J." last="Gill">Anthony J. Gill</name><name sortKey="Sidhu, Stan B" sort="Sidhu, Stan B" uniqKey="Sidhu S" first="Stan B." last="Sidhu">Stan B. Sidhu</name><name sortKey="Sidhu, Stan B" sort="Sidhu, Stan B" uniqKey="Sidhu S" first="Stan B." last="Sidhu">Stan B. Sidhu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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